CRED Understanding Clinical Development 2024

11/10/2024

Clinical Pharmacokinetics

October 2024

Marco Siccardi, ESQlabs

The Organisation for Professionals in Regulatory Affairs The Organisation for

Professionals i Regulatory Affairs

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Drug in tissue

Volume of distribution

Bioavailability

Drug in systemic circulation

Drug at the site of action

Dose

Clearance

Drug eliminated

Pharmacokinetics (what the body does to the drug)

Pharmacodynamics (what the drug does to the body)

The Organisation for Professionals in Regulatory Affairs

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