CRED Understanding Clinical Development 2024

11/10/2024

Precision Medicine – Identification of Factors Affecting Response

Precision medicine, also called

personalized medicine or

individualized medicine, takes

individual variation into account:

variation in our genes, environment,

lifestyle, and clinical data

Proper et al. 2021

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Ways to Accelerate Precision Medicine Implementation

• Data sharing to enable precision medicine

• Pharmacogenomics data application to personalized medicine. Development of genetic markers for drug response – for example, genetic link to pain threshold to support pain management studies

• Patient selection based on prognostic biomarkers

• Bayesian approaches to patient selection

• Modelling and simulations to evaluate potential strategies

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