Module 17 2024

03/12/2024

Challenges

A complex diagnostic pathway for CAD with multiple comparators

Digital health technology based application means that there are different versions of the software the incremental value of which needed to be taken into consideration especially since different studies were conducted with different versions of the software

The technology utilises a background computational process the impact of which to clinical outcomes needed to be taken into consideration

Relying on CCTA data to perform the analysis which is largely depended on local expertise

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Available comparators - HeartFlow

MRI

• Variability in clinical practice • Diagnostics tests for coronary artery disease (CAD) largely depended on expertise • Complex pathophysiology of coronary artery disease (CAD) • Different ways to diagnose CAD both structural and functional information • Often complementary information • Outcomes • Sensitivity and specificity of comparators largely depended on technical specifications of imaging modality • Technical and intermediate outcomes very important for HTA

PET

SPECT

Ultrasound

CT angiography

Invasive coronary angiography

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