Module 18 2021

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2/9/2021

Data collection: comprehensive searches

• Search strategy can introduce bias through missed data if not sufficiently: • Systematic • Sensitive • Specific Normally multiple databases should be used, to reduce risk of missing data.

Data collection: inclusion and exclusion criteria Bias can also be introduced through inappropriate selection criteria

• Which of the below are valid exclusion criteria?: • Animal studies • Studies > 5 years old • Non-clinical studies • Foreign language publications • Case studies or series • Studies which do not demonstrate endpoints met

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