Module 3 2019

Evidence of Chemical Structure (1)

Synthetic route – Comprehensive, Unequivocal, Resolution of isomers

Key intermediates – Contribution to stereochemistry – Retention of stereochemistry – Evidence of structure

➢ Spectroscopic evidence (with correct interpretation!) – UV-visible − IR – NMR: 1H, 13C, 15N, 31P − Mass – Other: Fluorescence, Raman

Nomenclature and Characterisationof the Active Ingredient

The Organisation for Professionals in Regulatory Affairs

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