Module 3 2019

Potential Isomerism: Asymmetric Carbons

➢ Two or more chiral centres

n centers - 2n isomers

−

Enantiomers as above

−

− Diastereoisomers - not mirror images: different properties − Epimer - change in configuration at one centre new diastereoisomer − Physical properties can be different

Nomenclature and Characterisationof the Active Ingredient

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