Module 3 2019

Ignore Polymorphism at Your Peril - 2!

➢ The solution:

o Much work and money spent o New interim soft gel formulation (refrigerated storage for bulks, not patients) to keep Form II in solution o New filings made January 1999 o Approved in US June 1999 and EU November 1999 ➢ Tablets (room temperature storage) not approved until 2009 (EU) or 2010 (USA)

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