Module 3 - Strategic case studies in practice

ICH Q3D(R1) Guideline

Mutagenesis 2002;17:411-7.

Monti-Bragadin C, Tamaro M, Banfi E. Mtuagenic activity of platinum and tuthenium complexes. Chem Biol Interact 1975;11:469-72. Schroeder HA, Mitchener M. Scandium, chromium (VI), gallium, yttrium, rhodium, palladium, indium in mice: Effects on growth and life span. J Nutr 1971;101:1431-8. Swartzendruber DC, Burnett IH, Wertz PW, Madison KC, Squier CA. Osmium tetroxide and ruthenium tetroxide are complementary reagents for the preparation of epidermal samples for transmission electron microscopy. J Invest Dermatol 1995;104(3):417-20. USDoL (OHSA). Occupational health guideline for osmium tetroxide. U.S. Department of Labor. 1978. USDoL (OHSA). 29 CRF 1910.1000 Table Z-1. Limits for air contaminants. U.S. Department of Labor. 2013 Wiseman CLS, Sereini F. Airborne particulate matter, platinum group elements and human health: A review of recent evidence. Sci Total Environ 20009;407:2493-500. Yasbin RE, Matthews CR, Clarke MJ. Mutagenic and toxic effects of ruthenium. Chem Biol Interact 1980:31:355-65.

65