Module 3 - Strategic case studies in practice

LOQ

Limit of Quantification

MA

Marketing Authorisation

MAH Marketing Authorisation holder Methyl-CCNU 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea MGMT Methyl-guanine-methyl-transferase MNNG N-Methyl-N´-nitro-N-nitrosoguanidine MS Mass Spectrometry ND Not detected NDBzA N-nitrosodibenzylamine NDEA N-Nitrosodiethylamine NDELA N-Nitrosodiethanolamine NDiBA N-Nitrosodiisobutylamine NDMA N-Nitrosodimethylamine NDPA N-Nitrosodi-n-propylamine NDPhA N-nitrosodiphenylamine NHMTC N-nitroso-2-hydroxymethyl-thiazolidine-4-carboxylic acid NHPRO N-nitrosohydroxyproline NIAN 1-Nitrosoindole-3-acetonitrile NLT Not less than NMEA N-Nitrosomethylethylamine NMNU N-Methyl-N-nitrosourea NMOR N-Nitrosomorpholine NMP N-Methyl-2-pyrrolidone NMT Not more than NMTCA N-nitroso-2-methyl-thiazolidine-4-carboxylic acid NMVA N-Nitrosomethylvinylamine NNK 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone NNN N-Nitrosonornicotine NOC(s) N-nitroso compound NPIC N-nitrosopipecolic NPIP N-Nitrosopiperidine NPRO N-nitrosoproline NPYR N-nitrosopyrrolidine

EMA/369136/2020

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