Module 3 - Strategic case studies in practice

Table 2.3.2-1 Physicochemical properties of some N-nitrosamines commonly studied (*: predicted, meridian; data obtained from US-EPA, CompTox Chemistry Dashboard, https://comptox.epa.gov/dashboard)

Water solubility

N- Nitrosamine Abbreviation

Structure

CAS

Log K ow

N- nitrosodi- methylamine

62-75-9

-0.57

13.5 mol/L

NDMA

N- nitrosodi- ethylamine

55-18-5

0.48

1.04 mol/L

NDEA

N- nitrosomethyl- ethylamine

10595-95-6

0.04

3.4 mol/L

NMEA

N- nitrosodi- propylamine

621-64-7

1.36

0.0999 mol/L

NDPA

N- nitrosodi- isopropylamine

NDIPA / DIPNA

601-77-4

1.38

0.0999 mol/L

N- nitrosoethyl- isopropylamine

NEIPA / EIPNA

16339-04-1

0.9

0.199* mol/L

N- nitrosodi- butylamine

924-16-3

2.63

0.008 mol/L

NDBA

N- nitrosomethyl- amino butyric acid

61445-55-4

-0,4*

2.29 mol/L*

NMBA

N- nitrosomethyl- phenylamine

614-00-6

1.49*

0.0494 mol/L*

NMPA / PMNA

N- nitrosomethyl-2- phenylethylamine

13256-11-6

1.55*

0.0212 mol/L*

EMA/369136/2020

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