Module 9 2021

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22/03/2021

HOW SIMILAR IS BIOSIMILAR?

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CHANGES TO PRODUCT QUALITY ATTRIBUTES

CEX chromatograms

Difference in basic variants

Difference in ADCC activity

Rituximab/Mabthera

Source: Schiestl, M et al (2011): Nature 29(4), 310 – 312.

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