Module232025

Pediatric Patient Acceptability Global Concern : o Medication non-adherence is recognized by WHO as a significant public health issue. Barriers to Adherence : o Influenced by age, cultural background, socioeconomic status, health literacy, and family structure. o Formulation-related factors include unpleasant taste, smell, mouthfeel, and appearance of medicines. Improving Acceptance : o Consider palatability (taste masking), dosing devices (spoons, syringes), and therapeutic schemes. o Perform acceptability tests during early clinical trials and pediatric formulation development. Innovative Solutions : o Technology offers potential tools for enhancing formulation acceptability and performance.

Quality (CMC) Development Considerations

The Organisation for Professionals in Regulatory Affairs