Module232025

12/05/2025

PSFs to date

PSF- 15

10-11 June, 2025 in Denver, USA

Antibody Drug Conjugates

The Organisation for Professionals in Regulatory Affairs

47

The FAIR Problem

18 year barier in clinical trial

Pediatric cancers with late onset Worse prognostic thanin children

Adult cancers with early onset Worse prognostic thanin adults

De Rojas et al JNCI 2019

Age (years)

18

Typical AYA onset Low improvment

…therapeutic trials are still governed by an 18year barrier

De Rojas et al, JNCI 2019

The Organisation for Professionals in Regulatory Affairs

48