CRED Understanding Clinical Development 2024

11/10/2024

Renal clearance

GLOMERULAR FILTRATION

TUBULAR SECRETION

REABSORPTION

The Organisation for Professionals in Regulatory Affairs

15

Tissue distribution and relevance of selected transporters

Brain Kidney Liver

Intestine

Peripheral blood cells

The Organisation for Professionals in Regulatory Affairs

Bleasby et al. Xenobiotica . 2006

16

8