Module 3 Presentations
07/05/2024
Potential Isomerism: Asymmetric Carbons
Two or more chiral centres n centers - 2n isomers Enantiomers as above Diastereoisomers - not mirror images: different properties Epimer - change in configuration at one centre new diastereoisomer Physical properties can be different
Nomenclature and Characterisation of the Active Ingredient
The Organisation for Professionals in Regulatory Affairs
25
Potential Isomerism: Other Geometric isomer (alkenes) Both carbon atoms forming the double bond are attached to two different groups E/Z isomers (cis/trans) Chirality associated with other elements Sulphur, Nitrogen, Phosphorus Positional isomers Ring substitution
Nomenclature and Characterisation of the Active Ingredient
The Organisation for Professionals in Regulatory Affairs
26
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